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The pilot had to depart from the planned route due to bad weather.

To deviate from a course or standard.
He had to depart from his promise.
The story can depart from the book.
Do not depart from the rules.
depart from the norm
depart from the truth
depart from the plan
deviate
swerve
stray
The train will depart from platform 3.

To leave or go away from a place.
We depart tomorrow morning.
The plane will depart soon.
Please depart quietly.
depart from
depart on time
depart the station
leave
exit
go