She learned how to operate the new computer.

To control or manage the functioning of a machine, device, or system.
He can operate the machine.
Can you operate this device?
They operate the business well.
operate a machine
operate a system
operate a business
run
control
manage
The surgeon will operate on the patient's knee tomorrow.

To perform a procedure or action, especially in a medical context.
The doctor will operate soon.
They operate on the injured.
He will operate the machine.
operate on
operate a machine
operate a business
perform
conduct
execute